Search results for "Statistical learning"

MODELLI DATA-DRIVEN VALORIZZAZIONE DELLE INFORMAZIONI DIGITALI A SUPPORTO DEI PROCESSI DECISIONALI DELLA SUPPLY CHAIN

2023

Biodegradability Prediction of Fragrant Molecules by Molecular Topology

2016

Biodegradability is a key property in the development of safer fragrances. In this work we present a green methodology for its preliminary assessment. The structure of various fragrant molecules is characterized by computing a large set of topological indices. Those relevant to biodegradability are selected by means of a hybrid stepwise selection method to build a linear classifier. This model is compared with a more complex artificial neural network trained with the indices previously found. After validation, the models show promise for time and cost reduction in the development of new, safer fragrances. The methodology presented could easily be adapted to many quasi-big data problems in R…

Aging effects and feasibility of statistical learning tasks across modalities

2021

Knowledge on statistical learning (SL) in healthy elderly is scarce. Theoretically, it is not clear whether aging affects modality-specific and/or domain-general learning mechanisms. Practically, there is a lack of research on simplified SL tasks, which would ease the burden of testing in clinical populations. Against this background, we conducted two experiments across three modalities (auditory, visual and visuomotor) in a total of 93 younger and older adults. In Experiment 1, SL was induced in all modalities. Aging effects appeared in the tasks relying on an explicit posttest to assess SL. We hypothesize that declines in domain-general processes that predominantly modulate explicit learn…

Learning, regularization and ill-posed inverse problems

2005

Many works have shown that strong connections relate learning from examples to regularization techniques for ill-posed inverse problems. Nevertheless by now there was no formal evidence neither that learning from examples could be seen as an inverse problem nor that theoretical results in learning theory could be independently derived using tools from regularization theory. In this paper we provide a positive answer to both questions. Indeed, considering the square loss, we translate the learning problem in the language of regularization theory and show that consistency results and optimal regularization parameter choice can be derived by the discretization of the corresponding inverse prob…

Development and validation of prediction model to estimate 10-year risk of all-cause mortality using modern statistical learning methods: a large pop…

2021

Abstract Background In increasingly ageing populations, there is an emergent need to develop a robust prediction model for estimating an individual absolute risk for all-cause mortality, so that relevant assessments and interventions can be targeted appropriately. The objective of the study was to derive, evaluate and validate (internally and externally) a risk prediction model allowing rapid estimations of an absolute risk of all-cause mortality in the following 10 years. Methods For the model development, data came from English Longitudinal Study of Ageing study, which comprised 9154 population-representative individuals aged 50–75 years, 1240 (13.5%) of whom died during the 10-year follo…

A Process-Oriented View of Procedural Memory Can Help Better Understand Tourette’s Syndrome

2021

Tourette’s syndrome (TS) is a neurodevelopmental disorder characterized by repetitive movements and vocalizations, also known as tics. The phenomenology of tics and the underlying neurobiology of the disorder have suggested that the altered functioning of the procedural memory system might contribute to its etiology. However, contrary to the robust findings of impaired procedural memory in neurodevelopmental disorders of language, results from TS have been somewhat mixed. We review the previous studies in the field and note that they have reported normal, impaired, and even enhanced procedural performance. These mixed findings may be at least partially be explained by the diversity of the s…

Learning-based multiresolution transforms with application to image compression

2013

In Harten's framework, multiresolution transforms are defined by predicting finer resolution levels of information from coarser ones using an operator, called prediction operator, and defining details (or wavelet coefficients) that are the difference between the exact and predicted values. In this paper we use tools of statistical learning in order to design a more accurate prediction operator in this framework based on a training sample, resulting in multiresolution decompositions with enhanced sparsity. In the case of images, we incorporate edge detection techniques in the design of the prediction operator in order to avoid Gibbs phenomenon. Numerical tests are presented showing that the …

Statistical learning and multiple linear regression model for network selection using MIH

2014

Award of Appreciation; International audience; A key requirement to provide seamless mobility and guaranteeing Quality of Service in heterogeneous environment is to select the best destination network during handover. In this paper, we propose a new schema for network selection based on Multiple Linear Regression Model (MLRM). A horough investigation, on a huge live data collected from GPRS/UMTS networks led to identify the Key Performance Indicators (KPIs) that play the most important role in the handover process. These KPIs are: Received Signal Code Power (RSCP), received energy per chip (Ec/No) and Available Bandwidth (ABW) of the destination network. To extract a handover model from col…

Similarity boosted quantitative structure-activity relationship--a systematic study of enhancing structural descriptors by molecular similarity.

2013

The concept of molecular similarity is one of the most central in the fields of predictive toxicology and quantitative structure-activity relationship (QSAR) research. Many toxicological responses result from a multimechanistic process and, consequently, structural diversity among the active compounds is likely. Combining this knowledge, we introduce similarity boosted QSAR modeling, where we calculate molecular descriptors using similarities with respect to representative reference compounds to aid a statistical learning algorithm in distinguishing between different structural classes. We present three approaches for the selection of reference compounds, one by literature search and two by…

Across space and time : infants learn from backward and forward visual statistics

2016

International audience; This study investigates whether infants are sensitive to backward and forward transitional probabilities within temporal and spatial visual streams. Two groups of 8-month-old infants were familiarized with an artificial grammar of shapes, comprising backward and forward base pairs (i.e. two shapes linked by strong backward or forward transitional probability) and part-pairs (i.e. two shapes with weak transitional probabilities in both directions). One group viewed the continuous visual stream as a temporal sequence, while the other group viewed the same stream as a spatial array. Following familiarization, infants looked longer at test trials containing part-pairs th…